Andrew Rowan: Forty-Three Years of 3Rs Advocacy

A celebration of the 60th Anniversary of the publication of The Principles of Humane Experimental Technique by W.M.S Russell and R.L. Burch. This event, which featured some of the eminent scientists and researchers in the field of alternatives to animal testing, took place on November 22, 2019 at the Johns Hopkins Bloomberg School of Public Health in Baltimore, Maryland.

The event was sponsored by CAAT, Foundation for Chemistry Research and Initiatives, Alternative Research & Development Foundation (ARDF), The American Cleaning Institute (ACI), International Fragrance Association (IFRA), Institute for In Vitro Sciences (IIVS), John “Jack” R. Fowle III, and the Society of Toxicology (SOT).

Personal Reflections

• Open Remarks: Andrew Rowan (WellBeing International)
John Parascandola (Department of History, University of Maryland College Park): “Origins of the 3Rs”
• Andrew Rowan (WellBeing International): "Forty-Three Years of 3Rs Advocacy"
• Michael Balls (University of Nottingham): "The Principles at 60: What Next?"
• Alan Goldberg (Johns Hopkins University): “The 3Rs: Recollections, Remembrances and Reminiscing”
• Horst Spielmann (Free University of Berlin): "Recent Advances in 3Rs Research: Human In Vitro Disease Models for Drug Development, Integrated Human Micro-Physiological Systems and 3Rs Centers Networks"
• Julia Fentem (Unilever): “Working Together to Replace Animal Testing for Assessing the Safety of Consumer Products: Pioneering Change, Building Confidence & Next Steps”
• Rodger Curren (Institute for In Vitro Sciences): “Mile Markers Along the 3Rs Path.”
• Rolf Bass (University of Berlin) "Pharmaceutical Development: LD 50 Elimination in the EU, and Impact of ICH on Animal Usage."
• Special Presentation

Looking Forward: the Future with 3Rs and CAAT’s Role on 3Rs for the 21st Century

• Nicole Kleinstreuer (NICEATM/NIEHS Interagency Center for the Evaluation of Alternative Toxicological Methods): “Balancing Big Data and Biology, Machine Learning and Mechanisms”
• Rusty Thomas (Environmental Protection Agency): “Building a Future for Chemical Safety Testing with the 3Rs”
• Katya Tsaioun (Johns Hopkins University): “Paradigm Change in 3Rs: Evidence-based Methods for Objective Tests Comparison”
• Kathrin Herrmann (Johns Hopkins University): “Refinement on the Way to Replacement: Are We Doing What We Can?” (CONTENT WARNING: Video of animals in severe distress)
• Thomas Hartung (Johns Hopkins University): “3Rs - Lessons into Actions”
Martin Stephens (Johns Hopkins University): “Bill and Rex: Rediscovery, Reunion, and Reinterpretation.”
• Closing Remarks: Martin Stephens (Johns Hopkins University)

© 2019 The Center for Alternatives to Animal Testing (CAAT)

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