Clinically recurrent episodes of wheezing,breathlessness,chest tightness and cough
Physiologically by widespread reversible narrowing of bronchial airways and a marked increase in bronchial responsiveness
Drugs used in management of bronchial asthma
1.Reduction of mast cell degranulation
Cromolyn/nedocromil
2.Reduction of cholinergic influence from vagal motor nerves
Antimuscarinic agents
3.Direct relaxation of airway smooth muscle
Sympathomimetic drugs
Theophylline
4.Leukotriene receptor antagonists
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